Organ-on-Chips for Studying Tissue Barriers: Standard Techniques and a Novel Method for Including Porous Membranes Within Microfluidic Devices

Introduction Organ-on-Chips for Studying Tissue Barriers - Disruption of cell-formed tissue barriers is an essential part of many diseases' pathophysiology.…

4 years ago

Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology

Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White adipose tissue (WAT)…

4 years ago

Upcoming Organ-on-a-chip Conferences

Find out about all the upcoming Organ-on-a-chip Conferences and how to get there. An organ-on-a-chip (OOC) is a multi-channel 3-D microfluidic…

4 years ago

A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease

Introduction Microfluidic 3D Endothelium-on-a-Chip - The endothelium is a thin membrane that lines the heart and blood vessels. Endothelial cells…

4 years ago

3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine

3D Microphysiological System Vascularized Tissue - Human vascular microphysiological systems (MPS) represent promising three-dimensional in vitro models of normal and…

4 years ago

Organ-on-a-Chip: A New Paradigm for Drug Development

Introduction Organ-on-a-Chip is a potential, multidisciplinary method for in-vitro modeling of disease, drug screening, and precision medicine that simulates in-vitro…

4 years ago

A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems

Introduction The extracellular matrix (ECM) is the non-cellular component present within all tissues and organs, which provides not only important…

4 years ago

Adipocyte-Endothelium Crosstalk in Obesity

Introduction The supporting vasculature is critical to the development of Adipose Tissue (AT) engineered models. Although it is essential for…

4 years ago

The vascular niche in next generation microphysiological systems

Introduction As a novel technology for in vitro toxicity testing platforms in recent years, Microphysiological Systems (MPS) have been actively…

4 years ago

Organ-on-chip applications in drug discovery: an end-user perspective

Introduction Organ-on-a-chip is regarded as a key new technology for research and development because it can predict how a potential…

4 years ago

Advanced models of human skeletal muscle differentiation, development and disease: 3D cultures, organoids and beyond

Introduction The organization and function of living muscle tissues cannot be fully recapitulated by typical two-dimensional (2D) culture methods in…

4 years ago

Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing

Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies. In the realm of…

4 years ago