Hepatocyte and Liver Tissue

Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing

Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies. In the realm of…

4 years ago

Liver microphysiological platforms for drug metabolism applications

Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant costs of…

4 years ago

A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation

Introduction Recently, microfluidics and 3D cell culture technologies have merged, to increase the potential of in vitro modeling, in order…

4 years ago

Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice (Ishida et al, 2021)

Introduction Adipose tissue-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are obtained from abundant adipose tissue, adherent on…

4 years ago

Experimental liver models: from cell culture techniques to microfluidic organs-on-chip (Polidoro et al, 2021)

Introduction - The Organ-on-a-Chip (OOAC) is a leading organ biomimetic (POB) device based on a microfluidic chip in the list…

4 years ago

Binding of the SARS-CoV-2 Spike Protein to the Asialoglycoprotein Receptor on Human Primary Hepatocytes and Immortalized Hepatocyte-Like Cells by Confocal Analysis (Collins DP et al, 2021)

Summary SARS-CoV-2 is the virus that caused the COVID-19 pandemic and its devastating effects on global health and economics. The…

4 years ago