Introduction MPS (Multiorgan Microphysiological Systems) have evolved from tools to reduce animal experimentation and improve preclinical toxicity assessments to an…
Introduction Melanoma is clearly a complex disease with a high degree of heterogeneity and adaptability. Melanoma cells are part of…
Introduction The researchers created a microfluidic organ-on-chip solution with integrated electrochemical microsensor arrays enabling compartmentalized matrix-based organoid culture from single…
Introduction Animal models and two-dimensional (2D) cell cultures frequently fail to replicate human drug metabolism and liver toxicity in vivo,…
Introduction Adipose Tissue is very versatile and essential for studies related to Obesity and Diabetes, however, the high buoyancy, fragility,…
Introduction The authors present a simple and modular Microphysiological system without the use of complex components consisting of 1) a…
Introduction Many Organ-on-Chip platforms are still not robust for all cell types, are not reproducible from experiment to experiment or…
Why a skin on a chip? The skin is the outer envelope of the body. It contains pressure, temperature, and pain…
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota, as well as the…
Introduction In vitro generation of perfusable 3D microvessels is an important goal for tissue engineering and reliable modeling of blood…
Introduction In postmenopausal women, fat mass and adipose-tissue mass (see Human Breast Adipocytes) are closely linked to obesity and breast…
Introduction Organ-on-Chips for Studying Tissue Barriers - Disruption of cell-formed tissue barriers is an essential part of many diseases' pathophysiology.…