Microenvironmental Control

Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology

Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White adipose tissue (WAT)…

4 years ago

A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease

Introduction Microfluidic 3D Endothelium-on-a-Chip - The endothelium is a thin membrane that lines the heart and blood vessels. Endothelial cells…

4 years ago

3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine

3D Microphysiological System Vascularized Tissue - Human vascular microphysiological systems (MPS) represent promising three-dimensional in vitro models of normal and…

4 years ago

Organ-on-a-Chip: A New Paradigm for Drug Development

Introduction Organ-on-a-Chip is a potential, multidisciplinary method for in-vitro modeling of disease, drug screening, and precision medicine that simulates in-vitro…

4 years ago

A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems

Introduction The extracellular matrix (ECM) is the non-cellular component present within all tissues and organs, which provides not only important…

4 years ago

The vascular niche in next generation microphysiological systems

Introduction As a novel technology for in vitro toxicity testing platforms in recent years, Microphysiological Systems (MPS) have been actively…

4 years ago

Organ-on-chip applications in drug discovery: an end-user perspective

Introduction Organ-on-a-chip is regarded as a key new technology for research and development because it can predict how a potential…

4 years ago

Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing

Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies. In the realm of…

4 years ago

Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME

Introduction Drug compounds' effectiveness, toxicity, and pharmacokinetics may be more accurately predicted in humans with the use of Organ-on-a-Chip technology.…

4 years ago

Liver microphysiological platforms for drug metabolism applications

Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant costs of…

4 years ago

A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation

Introduction Recently, microfluidics and 3D cell culture technologies have merged, to increase the potential of in vitro modeling, in order…

4 years ago