Adipocytes and Adipose Tissue

Co-culture With Human Breast Adipocytes Differentially Regulates Protein Abundance in Breast Cancer Cells

Introduction In postmenopausal women, fat mass and adipose-tissue mass (see Human Breast Adipocytes) are closely linked to obesity and breast…

4 years ago

Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology

Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White adipose tissue (WAT)…

4 years ago

A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease

Introduction Microfluidic 3D Endothelium-on-a-Chip - The endothelium is a thin membrane that lines the heart and blood vessels. Endothelial cells…

4 years ago

Adipocyte-Endothelium Crosstalk in Obesity

Introduction The supporting vasculature is critical to the development of Adipose Tissue (AT) engineered models. Although it is essential for…

4 years ago

Adipose Tissue-Endothelial Cell Interactions in Obesity-Induced Endothelial Dysfunction

Introduction Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation. Adipose Tissue regulates the production…

4 years ago

Adipocyte heterogeneity underlying adipose tissue functions

Introduction Adipose tissue does not only store energy, it also governs the metabolism of cells and tissues around the body…

4 years ago

Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice (Ishida et al, 2021)

Introduction Adipose tissue-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are obtained from abundant adipose tissue, adherent on…

4 years ago

Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance (Gallardo-Montejano et al, 2021)

Introduction - According to a recent study headed by UT Southwestern researchers, increasing a protein contained in brown fat appears…

4 years ago

Vascular smooth muscle-derived Trpv1+ progenitors are a source of cold-induced thermogenic adipocytes (Shamsi, F., Piper, M., Ho, LL. et al, 2021)

Introduction Brown fat is a kind of body fat that is activated when we get cold, also known as brown…

4 years ago

Insulin action in adipocytes, adipose remodeling, and systemic effects (Santoro et al, 2021)

Summary (Santoro et al) recognizes the essential importance adipocytes which react exquisitely to insulin have played in determining the mechanisms…

4 years ago

Obesity and COVID-19: Researcher Laurent Lagrost relies on the BCG vaccine to contain the inflammatory response in Adipose Tissue.

Laurent Lagrost, Research Director at Inserm (National Institute of Health and Medical Research) at the University of Burgundy in Dijon,…

4 years ago