Organs-on-a-chip

Liver Biopsies Beyond Histological Diagnosis: Ex-vivo Culturing and Precision Cut Slices for Precision Pharmacology

The Liver: Overview, Histology and Pathology  The liver (Fig. 1) is the largest organ in the human body and responsible…

5 years ago

LIVER BIOPSY ON CHIP

AIMS LIVER BIOPSY ON CHIPLiver Biopsy → Increase biopsies viability in long term culture liver biopsy → Imaging and biochemical quantification of…

5 years ago

In Vitro Immune Organs-on-Chip for Drug Development

Organs-on-Chip for Drug DevelopmentA drug should pass the preclinical evaluation phase to be FDA-approved. This relies (i) on in vitro…

6 years ago

Liver function and liver on a chip

The liver is a fundamental organ for human life. It is responsible for macromolecules (carbohydrates, fats, protein) metabolization and the…

6 years ago

Muscle on a Chip: State of the Art

Why a muscle on a chip? FUN FACT: Skeletal muscles account for 40% of the total body weight in humans…

8 years ago

Pancreas on a chip : State of the Art

Why a pancreas on a chip? The pancreas is an annex gland of the digestive system. It has both endocrine…

8 years ago

Heart on a chip: State of the Art

Why a heart on a chip? The heart is the central element of the cardiovascular system. If it is dysfunctional,…

8 years ago

Liver on a chip state of the art

Why a liver on a chip? The liver is part of the digestive tract, and the main organ involved in…

8 years ago

The complexity behind the 3D cell cultures: the 3D liver cell culture case

Introduction to 3D Liver Cell Culture Once it is clear how to deal with 3D cell cultures it is time…

8 years ago

From 2D to 3D cell cultures

Why and how? From 2D to 3D cell culture: The main issues find while using 2D cell systems, is that it…

8 years ago

Spheroids as powerul 3D-cell culture intermediates

Spheroids: What are they and what are their uses? In an organ, a cell needs to be considered together with…

8 years ago

Organotypic culture: from the beginning to 3D cell culture

What is the organotypic culture? Organotypic culture is defined as the culture of an organ collected from an organism. It…

8 years ago