Microenvironmental Control

Adipocyte heterogeneity underlying adipose tissue functions

Introduction Adipose tissue does not only store energy, it also governs the metabolism of cells and tissues around the body…

4 years ago

A new microfluidic method enabling the generation of multi-layered tissues-on-chips using skin cells as a proof of concept (Valencia et al, 2021)

Introduction Every organ is composed of a mesenchymal (stroma) and a parenchymal fraction. Conventional two-dimensional (2D) cultures are often focusing…

4 years ago

Rebuilding the Vascular Network: In vivo and in vitro Approaches (Meng et al, 2021)

Introduction The vascular network carries the transportation of materials and nutrients as the fluid delivery mechanism of the human body.…

4 years ago

Review on the Vascularization of Organoids and Organoids-on-a-Chip (Xingli and Zilu et al, 2021)

Introduction Organoids and organs-on-a-chip (vascularized 3d culture) have seen rapid growth in recent years due to their importance in mimicking…

4 years ago

Tumor microenvironment (TME)

The tumor microenvironment (TME) is a complex biochemical network that includes multiple factors surrounding tumor cells, such as vascular networks,…

6 years ago

Perfusion systems: continuous medium flow for cell culture

Perfusion systemsLong-term imaging of cultured cells requires controlled environmental conditions. Continuous perfusion of the medium allows maintaining cells under optimal…

6 years ago

Live-cell and perfusion: weak protein-protein interactions

Weak protein-protein interaction in live-cells Weak protein-protein interactions are a common phenomenon inside cells. Besides being well known, it has…

7 years ago