Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White adipose tissue (WAT) is a key regulator of whole-body metabolism and energy balance,…
Introduction The supporting vasculature is critical to the development of Adipose Tissue (AT) engineered models. Although it is essential for AT function and long-term maintenance, the Adipocyte-Endothelium Crosstalk is poorly…
Introduction As a novel technology for in vitro toxicity testing platforms in recent years, Microphysiological Systems (MPS) have been actively developed. MPS are cultural techniques for the rebuilding of human…
Introduction Organ-on-a-chip is regarded as a key new technology for research and development because it can predict how a potential medication will behave in human tissue structures – rather than…
Introduction The organization and function of living muscle tissues cannot be fully recapitulated by typical two-dimensional (2D) culture methods in skeletal muscle-derived cells, reducing their use in extensive physiological research.…
Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies. In the realm of drug research and discovery, they both have interesting applications. In…
Introduction PDMS, often known as dimethylpolysiloxane or dimethicone, is a silicone polymer. There are various uses for PDMS owing to its flexibility and characteristics. Although PDMS is a very good…
Introduction Drug compounds' effectiveness, toxicity, and pharmacokinetics may be more accurately predicted in humans with the use of Organ-on-a-Chip technology. Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models are the future of emulating…
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant costs of drug development. Toxicology or lack of efficacy are two of…
Introduction The vascular network carries the transportation of materials and nutrients as the fluid delivery mechanism of the human body. Tissue engineering research, therefore, focuses primarily on the forming of…