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Read more about the article Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology
Vascularized-3d-biological-model

Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology

Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White adipose tissue (WAT) is a key regulator of whole-body metabolism and energy balance,…

Continue ReadingIsolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology
Read more about the article A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease

A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease

Introduction Microfluidic 3D Endothelium-on-a-Chip - The endothelium is a thin membrane that lines the heart and blood vessels. Endothelial cells secrete chemicals that regulate vascular relaxation and contraction, as well…

Continue ReadingA Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease
Read more about the article 3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine

3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine

3D Microphysiological System Vascularized Tissue - Human vascular microphysiological systems (MPS) represent promising three-dimensional in vitro models of normal and diseased vascular tissue. These systems, which mimic essential functional components…

Continue Reading3D Microphysiological System- Vascularized Tissue Constructs for Regenerative Medicine
Read more about the article Organ-on-a-Chip: A New Paradigm for Drug Development

Organ-on-a-Chip: A New Paradigm for Drug Development

Introduction Organ-on-a-Chip is a potential, multidisciplinary method for in-vitro modeling of disease, drug screening, and precision medicine that simulates in-vitro physiology and pathology. Organ-on-a-Chip: A New Paradigm for Drug Development?Organ-on-a-chip…

Continue ReadingOrgan-on-a-Chip: A New Paradigm for Drug Development
Read more about the article A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems

A Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems

Introduction The extracellular matrix (ECM) is the non-cellular component present within all tissues and organs, which provides not only important physical support in cellular elements but also initiates key biochemicals…

Continue ReadingA Review of Biomaterials and Scaffold Fabrication for Organ-on-a-Chip Systems
Read more about the article The vascular niche in next generation microphysiological systems

The vascular niche in next generation microphysiological systems

Introduction As a novel technology for in vitro toxicity testing platforms in recent years, Microphysiological Systems (MPS) have been actively developed. MPS are cultural techniques for the rebuilding of human…

Continue ReadingThe vascular niche in next generation microphysiological systems
Read more about the article Organ-on-chip applications in drug discovery: an end-user perspective

Organ-on-chip applications in drug discovery: an end-user perspective

Introduction Organ-on-a-chip is regarded as a key new technology for research and development because it can predict how a potential medication will behave in human tissue structures – rather than…

Continue ReadingOrgan-on-chip applications in drug discovery: an end-user perspective
Read more about the article Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing

Kidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing

Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies. In the realm of drug research and discovery, they both have interesting applications. In…

Continue ReadingKidney Organoid and Microphysiological Kidney Chip Models to Accelerate Drug Development and Reduce Animal Testing
Read more about the article Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems

Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems

Introduction PDMS, often known as dimethylpolysiloxane or dimethicone, is a silicone polymer. There are various uses for PDMS owing to its flexibility and characteristics. Although PDMS is a very good…

Continue ReadingBeyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems
Read more about the article Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME

Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME

Introduction Drug compounds' effectiveness, toxicity, and pharmacokinetics may be more accurately predicted in humans with the use of Organ-on-a-Chip technology. Pharmacokinetics-On-a-Chip: In Vitro Microphysiological Models are the future of emulating…

Continue ReadingPharmacokinetics-On-a-Chip: In Vitro Microphysiological Models for Emulating of Drugs ADME
Read more about the article Liver microphysiological platforms for drug metabolism applications

Liver microphysiological platforms for drug metabolism applications

Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant costs of drug development. Toxicology or lack of efficacy are two of…

Continue ReadingLiver microphysiological platforms for drug metabolism applications
Read more about the article A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation

A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation

Introduction Recently, microfluidics and 3D cell culture technologies have merged, to increase the potential of in vitro modeling, in order to get even closer to human physiology. Control of the…

Continue ReadingA versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation
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