Introduction Animal models and two-dimensional (2D) cell cultures frequently fail to replicate human drug metabolism and liver toxicity in vivo, therefore there is a need for 3D Culture of HepaRG…
Introduction The gut-liver axis is the bidirectional interaction that exists between the gut and its microbiota, as well as the liver, and is the outcome of the integration of signals…
Introduction Kidney Organoid and Microphysiological Kidney Chip Models, both have their own unique advantages and deficiencies. In the realm of drug research and discovery, they both have interesting applications. In…
Introduction Liver microphysiological platforms for drug metabolism applications are the need of the hour to fix the exorbitant costs of drug development. Toxicology or lack of efficacy are two of…
Introduction Recently, microfluidics and 3D cell culture technologies have merged, to increase the potential of in vitro modeling, in order to get even closer to human physiology. Control of the…
Introduction Adipose tissue-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks can be expanded in vitro, and have the…
Introduction - The Organ-on-a-Chip (OOAC) is a leading organ biomimetic (POB) device based on a microfluidic chip in the list of the top ten innovative technologies. The microenvironment of the…
Summary SARS-CoV-2 is the virus that caused the COVID-19 pandemic and its devastating effects on global health and economics. The virus's transmission and pathology appear to be mediated through the…