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Read more about the article Melanoma Immunotherapy and Precision Medicine in the Era of Tumor Micro-Tissue Engineering: Where Are We Now and Where Are We Going?

Melanoma Immunotherapy and Precision Medicine in the Era of Tumor Micro-Tissue Engineering: Where Are We Now and Where Are We Going?

Introduction Melanoma is clearly a complex disease with a high degree of heterogeneity and adaptability. Melanoma cells are part of a larger ecosystem in which the tumor microenvironment influences their…

Continue ReadingMelanoma Immunotherapy and Precision Medicine in the Era of Tumor Micro-Tissue Engineering: Where Are We Now and Where Are We Going?
Read more about the article Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures

Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures

Introduction The researchers created a microfluidic organ-on-chip solution with integrated electrochemical microsensor arrays enabling compartmentalized matrix-based organoid culture from single stem cells and real-time recording of metabolic data. These patient-derived…

Continue ReadingMicrofluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures
Read more about the article A new microfluidic method enabling the generation of multi-layered tissues-on-chips using skin cells as a proof of concept

A new microfluidic method enabling the generation of multi-layered tissues-on-chips using skin cells as a proof of concept

Introduction The state of the art for tissues-on-chips using skin cells had been lacking for a long time due to the absence of both an epithelial and a stromal component…

Continue ReadingA new microfluidic method enabling the generation of multi-layered tissues-on-chips using skin cells as a proof of concept
Read more about the article Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology
Vascularized-3d-biological-model

Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology

Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White adipose tissue (WAT) is a key regulator of whole-body metabolism and energy balance,…

Continue ReadingIsolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-on-Chip Technology
Read more about the article The vascular niche in next generation microphysiological systems

The vascular niche in next generation microphysiological systems

Introduction As a novel technology for in vitro toxicity testing platforms in recent years, Microphysiological Systems (MPS) have been actively developed. MPS are cultural techniques for the rebuilding of human…

Continue ReadingThe vascular niche in next generation microphysiological systems
Read more about the article Organ-on-chip applications in drug discovery: an end-user perspective

Organ-on-chip applications in drug discovery: an end-user perspective

Introduction Organ-on-a-chip is regarded as a key new technology for research and development because it can predict how a potential medication will behave in human tissue structures – rather than…

Continue ReadingOrgan-on-chip applications in drug discovery: an end-user perspective
Read more about the article Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems

Beyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems

Introduction PDMS, often known as dimethylpolysiloxane or dimethicone, is a silicone polymer. There are various uses for PDMS owing to its flexibility and characteristics. Although PDMS is a very good…

Continue ReadingBeyond Polydimethylsiloxane (PDMS): Alternative Materials for Fabrication of Organ-on-a-Chip Devices and Microphysiological Systems
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