Introduction Adipose Tissue is very versatile and essential for studies related to Obesity and Diabetes, however, the high buoyancy, fragility, and heterogeneity of primary adipocytes have largely prevented their use…
Introduction In postmenopausal women, fat mass and adipose-tissue mass (see Human Breast Adipocytes) are closely linked to obesity and breast cancer. Adipocytes have the ability to modulate the tumor microenvironment…
Introduction Obesity and obesity-related co-morbidities are on the rise globally, necessitating the development of novel treatments. White adipose tissue (WAT) is a key regulator of whole-body metabolism and energy balance,…
Introduction Microfluidic 3D Endothelium-on-a-Chip - The endothelium is a thin membrane that lines the heart and blood vessels. Endothelial cells secrete chemicals that regulate vascular relaxation and contraction, as well…
Introduction The supporting vasculature is critical to the development of Adipose Tissue (AT) engineered models. Although it is essential for AT function and long-term maintenance, the Adipocyte-Endothelium Crosstalk is poorly…
Introduction Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation. Adipose Tissue regulates the production of hormones, angiogenic factors, and cytokines. During the development of…
Introduction Adipose tissue does not only store energy, it also governs the metabolism of cells and tissues around the body by secreting hormones, cytokines, proteins, and microRNA. Adipose tissue is…
Introduction Adipose tissue-derived stem cells (ADSCs) are mesenchymal stem cells (MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks can be expanded in vitro, and have the…
Introduction - According to a recent study headed by UT Southwestern researchers, increasing a protein contained in brown fat appears to lower blood sugar, enhance insulin sensitivity, and protect against…
Introduction Brown fat is a kind of body fat that is activated when we get cold, also known as brown adipose tissue. It generates heat to keep our body temperature…
Summary (Santoro et al) recognizes the essential importance adipocytes which react exquisitely to insulin have played in determining the mechanisms for insulin action on a cellular level on this hundredth…
Laurent Lagrost, Research Director at Inserm (National Institute of Health and Medical Research) at the University of Burgundy in Dijon, was among the first to warn of the coronavirus epidemic's…