3D In vitro contract research services

Which service do we provide ?

Discover the Catalog

We offer a diverse portfolio of biology models testing services to improve the likelihood of success in your clinical trials. Below is a list of our standard application offerings.

biological model	biological features	readouts	applications
LIVER ORGANOIDS	VASCULARIZATION DIFFERENTIATED FUNCTIONAL ENDOTHELIUM SMART SPHEROPLATE ® MEDIUM PERFUSION STRONG/ NO GRADIENT NORMIXIA HYPOXIA CIRCULATING MONOCYTES FULLY RECONSTRUCTED HUMAN EPIDERMIS IMMUNOCOMPETENT CIRCULATING MONOCYTES NATURAL KILLER T-CELL RESIDENT IMMUNITY MACROPHAGE (M0 M1, M2) SPECIALIZED IMMUNE CELLS "KUPFFER" (RESIDENT DENDRITIC CELL) ALTERATED/ NORMAL ENDOTHELIUM PERMABILITY ASSOCIATED CELLS (FIBROBLAST, ADIPOCYTE EXTRA CELLULAR MATRIX (ECM, COLLAGEN, MATRIGEL, COMMERCIAL MATRIX)	MICROSCOPY CONFOCAL IMMUNO LABELLING LIVE/ DEAD ASSAY IMMUNOCYTO-CHEMISTRY RTQPCR OXYGEN CONSUMPTION LACTATE GLUCOSE PRODUCTION/ CONSUMPTION LIVE IMAGING (MASS VARIATION, CELL MIGRATION)	DILI (DRUG INDUCED LIVER INJURY) IMMUNO MEDIATED DILI
FULLY DIFFERENTIATED SKIN			BIOCOMPABILITY (ISO 10993) IRRITATION VS OECD SENSITIZATION VS OECD TG 442E
melanoma equivalent			DMPK (liver metabolization, tumor penetration) Pharmacology (target validation, efficacy study) toxicology (bystander effect)
tumoroids
breast
lung

How does it work?

Cherry Biotech’s CRO service is a step by step process designed to provide customers with accurate and reliable in vitro data for drug development:

Discuss with our experts to determine the best models for your project (either yours, or pick from our models catalog)
Select the Model
Determine the set of readouts, types of cells and experimental plan
We perform the study using our Microphysiological system CubiX to accurately mimic a vascularized human organ in vitro
Receive a full report with the option to obtain cell and medium samples

Discuss your project vision with our expert

Select the Model

Select the set of Readouts, Types of cells & Experiment plan

Experiment

We perform the study using our Microphysiological system (MPS) CubiX to accurately mimic a vascularized human organ in 3D virto

Deliverable

Why
3D invitro ?

With the change in regulations that no longer require animal testing models as compulsory, there is a growing anticipation of 2D/3D models as an alternative for drug testing.

Our service offers a great solution that respects animal welfare and experiment ethics while providing a competitive advantage for clients in drug development.

By utilizing our CRO 3D in-vitro activity testing and CubiX microphysiological system, clients can achieve greater accuracy and precision without the need for animal testing. With a focus on moral values and innovation, our service offers a more ethical and efficient approach to drug development.

service highlights

Our CRO service provides standard and custom in vitro studies using organ-on-a-well (OOW) technology to support drug development.

Our service highlights:

Human-relavant 3D in vitro models

Our Microphisiology technology generates human-relevant data that is more predictive of clinical outcomes compared to animal studies.

Access to OOW technology without investing in equipment

Save time and resources by outsourcing your in vitro studies to our team of experts who have the necessary equipment and expertise to conduct experiments.

Time saving & cost-effective results

Our team works with you to design and execute studies that yield results quickly and cost-effectively compared to traditional animal studies.

Cutting-edge expertise in Organ-on-Well technology

Our patented Organ-On-Well technology allows full- compatibility with the industry standard. Combine with the meticulous knowledge of our team of scientists, we can provide your team valuable insights and recommendations to improve your drug development programs.

Proven track record for delivering clinically translatable results

We have a history of providing results that are translatable to clinical outcomes, which can help you progress your drug candidates towards successful clinical trials.

start a project with us

Partner with us to accelerate your drug development program and increase your chances of clinical success.

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