A new microfluidic method enabling the generation of multi-layered tissues-on-chips using skin cells as a proof of concept (Valencia et al, 2021)

Introduction Every organ is composed of a mesenchymal (stroma) and a parenchymal fraction. Conventional two-dimensional (2D) cultures are often focusing on the mimicking of the parenchymal fraction (eg, hepatocytes, enterocytes,…

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OOCHIP: Compartmentalized Microfluidic Perfusion System with Porous Barriers for Enhanced Cell-Cell Crosstalk in Organ-on-a-Chip (Ramadan et al)

Abstract: (Ramadan et al) : Improved in vitro models of human organs for predicting drug efficacy, interactions, and disease modeling are crucially needed to minimize the use of animal models,…

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Introduction to the human body

The human body: systems, organs, and main functions The human body is composed of several different subsystems ranging from microscopic scales to macroscopic levels. All the functions are controlled by…

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LIVER BIOPSY ON CHIP

AIMS LIVER BIOPSY ON CHIPLiver Biopsy → Increase biopsies viability in long term culture liver biopsy → Imaging and biochemical quantification of drug effect → Interface blood vessel/hepatocyte → DILI assessment based on…

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