CubiX

Made with passion for type 2 diabetes physio-pathology

We believe in changing the paradigm of preclinical study to

⚕️ Accelerate the development of personalized medicine
💊 Better predict a drug effect on a human body
🐁 Accelerate the development of an alternative to animal models

The way we are changing it is by using the power of industrialized microfluidic to mimick a physio-pathology of a human body in vitro

We design MicroPhysiological Systems compatible with a multiwell standard

Untitled design (15)
CherryBiotech-cubix-cells-biopsy

Main Features

PDMS_Chip
PDMS free

The only commercial MPS PDMS free device with no bias in toxicology and efficacy studies

incubator
Incubator free

Direct integration in existing analysis workflow, without disruption of the culture conditions

Pré-clinical, 3D Culture & In Vitro Tox
Compatible with culture standard

From 6 to 24 well allowing a direct transfer of the culture protocol

Vascularized-3d-biological-model
Vascularized 3D biological model

Physiological maintenance of a differentiated endothelium with an organ stroma >5 days

Discover the Applications of Cubix

Our Experience

Our mission is to develop the most advanced technological platform for predicting the impact of molecules (drug, endocrine disruptor, cosmetic, etc.) on the human body to better treat pathologies (orphan diseases, cancer, bacterial resistance, virus). Moreover, This platform is an alternative to use less animals model by combining new microfluidic technology , artificial intelligence and most advanced imaging techniques.

Cubix-3D-Adipocyte-Culture-Microphysiologcal-Controller

Testimonials

Learn how Cubix impacted researchers, the first incubator-free microenvironment controller in the world. Enabled the mimicking of physiological and pathological culture conditions in vitro. CubiX is the only microenvironment controller fully compatible with live imaging. You will never be blind to your sample ever.

CubiX is scalable & customizable allowing you to use custom made chips, multiwell, commercial microfluidic chip, and many more to help you get better and longer biological culture.

Cubix and its consumables compatible with multi-well plates are versatile and do not upset the operative praxis of biomedical researchers. Further, the consumable can be configurated with a high customizable interconnection layout of the wells ensuring desired intra- and inter-well gradients.
Matteo BONINSEGNA
PHD STUDENT / H2020-ITN-DELIVER
Cubix! This cube fixes everything that I wished for. Cubix empowered us in replicating effortlessly the microenvironment conditions for spermatozoa swimming. Customized physiological gases enrichment with high degree control of flow and temperature allowed us to develop a repeatable, user-friendly, and automated biological protocol
Shiva K SHUKLA, PhD
Post-doc Marie Curie Individual Fellowship, project MicroFSMA
An easy to grasp user interface and near-complete plug-n-play assembly allows for using low-to-medium throughput consumables. Customizable liquid flow patterns allow for easy micro-tissue and multi-organ zonation designs.
François TAUTE, PhD
Post-doc Marie Curie Individual Fellowship, project Mimetic Indirect
I thoroughly enjoyed working with CubiX, and particularly appreciated that I could control the dissolved oxygen in the culture unit. This I then could also monitor through the systems compatibility with in-line sensors.
Miriam GRAUTE, PhD
PHD STUDENT / H2020-ITN EID-GROWTH

We Are Here For You

Projects - 15
Partners - 150
Beta testers - 5

Cubix for Pharmaceautical and Biotech Companies

  • Benefits: Lower false positive drug candidate in preclinical phases, accelerate the drug development process, leading to drastic cost reduction
     
  • How?:  Obtain a functional 3D vascularized adipose tissue  in medium-throughput, for a hit to lead and lead characterization

Cubix for Academic and Translational Researchers

  • Benefits: New fundamental discovery leading to higher publications impact and increase Shanghai ranking
     
  • How?: Obtain a functional 3D vascularized adipose tissue long term (> 2weeks) for new molecular target identification and mechanism of action deciphering

Diabetes Knowlegde Centre

Type 2 Diabetes Mellitus: Evaluating the Safety of New Drugs for Improving Glycemic Control Guidance for Industry
The International Diabetes Federation (IDF) is an umbrella organization of over 230 national diabetes associations in 170 countries and territories. It represents the interests of the growing number of people with diabetes and those at risk
Understanding medicine -Type 2 diabetes
World Health Organization Diabetes Fact Sheet
With diabetes, knowledge is power. Explore this collection of articles created for people with diabetes or who are at risk for diabetes, and their families and friends.
The European Medicines Agency (EMA) is a decentralised agency of the European Union (EU). It began operating in 1995. The Agency is responsible for the scientific evaluation, supervision and safety monitoring of medicines in the EU.